Polynucleotides are some of the most popular treatment options to hit the aesthetics market. With the ability to revitalise the skin deeply from the inside out, they are quickly becoming a go-to for skin repair and radiance. But what exactly are they, and how do they work?
What are polynucleotides?
Polynucleotides are injectable treatments designed to promote skin regeneration, repair and overall skin health at a cellular level. Unlike conventional alternatives such as skin boosters that primarily provide hydration, polynucleotides actively stimulate fibroblasts – the cells responsible for producing collagen and maintaining connective tissue. This results in cell turnover, tissue repair and the production of collagen and elastin.
What are polynucleotides made from?
Polynucleotides are typically derived from highly purified DNA sourced from the sperm of fish such as salmon. They are biocompatible with human tissue due to their close structural resemblance to human DNA. This compatibility enables them to effectively initiate natural healing responses within the skin, making them valuable for addressing a range of dermatological concerns including scarring, signs of ageing, inflammation, and pigmentation issues.
What is the difference between polynucleotides and PDRN?
The term PDRN (Polydeoxyribonucleotide) may also appear in discussions related to polynucleotide treatments. PDRN is a subtype of polynucleotides and shares many of the same benefits, such as healing and rejuvenation. However, polynucleotides in general (particularly those used in aesthetic medicine) are often more purified and concentrated, offering long lasting and durable results.
Benefits of polynucleotides
Acne scarring
By stimulating collagen production and enhancing tissue regeneration, polynucleotides can significantly improve the skin’s texture and reduce the appearance of scars left by acne.
Rosacea
Polynucleotides help to strengthen the skin barrier, which can reduce sensitivity, calm inflammation, and alleviate visible symptoms commonly associated with rosacea.
Fine lines & wrinkles
Through the activation of fibroblasts, polynucleotides promote collagen and elastin synthesis, leading to firmer, smoother skin and a noticeable reduction in fine lines and deeper wrinkles.
Hyperpigmentation
These treatments can help regulate melanin production, helping to fade existing dark spots and minimising the formation of future pigmentation irregularities.
Hydration & rejuvenation
Due to their ability to attract and retain water, polynucleotides improve skin hydration levels while supporting overall rejuvenation, resulting in a more radiant and revitalised complexion.
How long does it take to see results?
You can expect to see results with polynucleotides within 3-5 weeks following treatment. For optimal outcomes, a course of 3 sessions is generally recommended. Multiple sessions allow for sustained fibroblast stimulation and help prolong the effects of the treatment.
How long do results last?
The results of polynucleotide treatments can last anywhere between 12-18 months. This however is dependant on individual factors such as skin condition, age and lifestyle.
Polynucleotide treatments at The Medical Hub
Here at The Medical Hub, we offer polynucleotide treatments designed to restore and revitalise your skin from within. Each appointment is tailored to your individual needs, beginning with a comprehensive consultation where a practitioner will review your medical history, discuss your treatment goals and answer any questions you may have. The procedure itself typically takes between 30-60 minutes depending on the number of areas being treated. Get started by booking an appointment today at our Liverpool clinic.
